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Fig. 2. D-mib is required for multiple Neur-independent, Notch-dependent developmental processes. (A,C,E,G,I,K) Wild-type; (B,D,F,H,J,L) D-mib¹ homozygotes. D-mib¹ pharate adults are largely eyeless (B) and wingless (D). D-mib mutants (F) also display defective leg development and lack joints (arrows compare with E). Leg structures are abbreviated as follows: Ti, tibia; t1-t5, the five tarsal segments; cl, claw. (G-L) Wing imaginal discs stained for Nubbin (G,H), Cut (I,J) and Senseless (K,L). Note that wing margin (WM) expression of Cut and Senseless is absent in D-mib¹ discs, but that sensory organ precursors (arrows) are singularized normally in this mutant.

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