|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 5. Apoptosis in the inner ear of mgRb:Rb-/- mutants at
E18.5. (A-C) In a mutant cochlea, the myosin VI-stained region of
supernumerary HCs, which comprises mitotic figures (A, short arrows), shows
TUNEL-(B) and cleaved caspase 3-(C) positive cells. Views are from adjacent
sections. Compare with normal morphology in
Fig. 2A. (D-F) TUNEL- and
caspase 3-positive cells are present in the myosin VI-stained region of a
hyperplastic utricular sensory epithelium. Compare with normal morphology in
Fig. 3A. Long arrows indicate
apoptotic profiles. Abbreviations: co, cochlea; ut, utricle; myo, myosin VI;
casp, cleaved caspase 3. Scale bar: 60 µm.
|
