|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 2. Alterations of the size of the neural plate in Xsix3 gain- and
loss-of-function experiments. (A-H,K-Z) Embryos injected unilaterally with
Xsix3 (A-H,K-N), GR-Xsix3 (O-R), VP16-Xsix3 (S-V)
or MoXsix3 (W-Z), and analysed at early neurula stage. The probes
used are indicated in each panel. Red staining in A,B,D-H,K-Z and turquoise
staining in C represent expression of the co-injected lacZ lineage
tracer. The injected side of the embryos (to the right of dotted lines
representing the midline) is indicated (inj). (A-G,K-M,O-Z) Frontal views,
dorsal towards the top; (H,N) ventral views (VV), anterior towards the bottom.
(H,N) Arrows indicate Xk81 repression caused by Xsix3
overexpression. (I,J) Embryos untreated (I) or treated (J) with HUA, brown
nuclear staining representing anti-phosphorylated histone H3 staining; dorsal
views, anterior towards the bottom. (K-N) Embryos injected with Xsix3
and treated with HUA. (A,B,K) White brackets indicate the anterior expression
of Sox2 (A,K) or Xnrp1 (B) in Xsix3-injected
(right) and control (left) sides.
|
