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Fig. 5. The cholinergic neurons express the P2X7 receptors and
accumulate ATP in granules, which suggests that they could be sources of
e-ATP. (A) In the neonatal rat retina the cholinergic cells (red) express the
P2X7 receptors (green), as do many retinal ganglion cells. Confocal
image of a P4 retinal section. (B-D) Quinacrine, which labels high levels of
ATP stored in granules, is found in the cholinergic cells. (B) Confocal image
of a P8 rat cholinergic neuron labeled with Alexa Fluor 568 dextran. (C) A
higher magnification of the same cell shows that its soma (red) contains
quinacrine labeling (green), which is also shown in isolation in D. Scale bar:
20 µm (A); 40 µm (B); 10 µm (C,D).
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