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Fig. 9. Summary of retinotectal mutants. The 13 loci are predicted to affect
different aspects of tectal development and architecture. The ddl
protein is required for differentiation of most RGCs. The vrt, tard
and late gene products ensure timely innervation of the tectum.
Products of vrt and coma organize the fascicles in the optic
tract, while bluk, clew, blin and coma regulate fiber-fiber
interaction in the tectum. Proteins encoded by fuzz, beyo and
brek confine axons to the neuropil, while drg is required
for targeting axons to the SFGS. (The deeper layers of the tectum, SGC and
SAC/SPV, are not labeled by Brn3c:mGFP.)
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