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Fig. 5. Expression of Igfbp5 in the hair follicle reduces the number of
medulla columns. Transgenic expression of Igfbp5 in hair follicles
during the growth phase using the involucrin promoter decreases the length of
hair shafts (top) and reduces the number of air space columns to one (bottom).
The extraordinary thinness of hair shafts severely hampered the isolation of
intact hairs. Thus, the presence of auchene hairs could not unequivocally be
confirmed.
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