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Fig. 7. Inhibition of TGFß signaling increases proliferation in P6 retinal explants. (A,B) BrdU labeling of P6 explants cultured as whole, floating retinas for 24 hours with BrdU, in control media, including mouse IGG (A) or in the presence of monoclonal antibody against TGFß ligands 1, 2 and 3 (B). Treatment with anti-TGFß antibody resulted in a 170.8% (±18.9) increase in the percentage of cells that were BrdU+, compared with control. *P<0.01, pairwise comparison (Student's t-test).





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