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Fig. 4. Hdac1, p27 and {Delta}N-Tcf3 suppress add- or Wnt-mediated retinal proliferation. Left bars (red, blue) indicate the ratio of the number of BrdU-positive cell clusters to total number of cell clusters in add mutant retinal cells expressing EGFP (n=39), Hdac1 (n=58), p27 (n=43) and {Delta}N-Tcf3 (n=148). Right bars (grey) indicate the ratio of the number of BrdU-positive cell clusters to total number of cell clusters in wild-type retinal cells co-expressing {Delta}47-ß-catenin and EGFP (n=23), and wild-type retinal cells co-expressing {Delta}47-ß-catenin and Hdac1 (n=48). *P<0.05 and **P<0.01 versus control; {chi}2-test.





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