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Fig. 5. Genome scan of 123 backcross Dax1-/Y fetuses scored as 0 for male, 1 for hermaphrodite and 2 for female (A). Genome scan including only 17 male and 19 female backcross Dax1-/Y fetuses (B). (A,B) The y-axis provides the LOD score and the x-axis indicates the genomic location in genetic map units (cM) with chromosome numbers indicated. An allele interaction plot for Chrs 1 and 8 (C). The y-axis is scaled such that 0 represents male, 0.5 represents hermaphrodite and 1 represents female. The effect of Chr 8 on the tendency to produce females differs depending on the allelic stage of Chr 1, and Chr 1 has an effect on the sex ratio only when the Chr 8 locus is heterozygous. The lines in the plot indicate homozygosity B (B; open circles) and heterozygosity B/D (D; squares) for the Chr 1 locus.





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