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Fig. 5. No evidence for alternate endocrine fate choices in Nkx6 compound mutants. Immunofluorescence staining for somatostatin (A-D), pancreatic polypeptide (PP) (E-H) and ghrelin (I-L) in pancreas from wild-type, Nkx6.2-/-, Nkx6.1-/-, and Nkx6.1-/-;Nkx6.2-/- embryos at E18.5. Wild type and Nkx6 compound mutants have similar numbers of somatostatin+, PP+ and ghrelin+ cells. Scale bar: 50 µm.





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