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Fig. 5. GLI1-induced tumorigenesis requires endogenous Gli1 and Gli3 function. (A) Tadpoles injected with human GLI1 and each MO. Arrows show tumors in tadpoles injected with GLI1 and MO-C or MO-2. (B) Sets of tadpoles injected with GLI1 and MO-C or MO-3 showing varying overall deformities present in tumor-bearing GLI1+MO-C-injected embryos but absent in GLI1+MO-3-injected siblings. The ß-gal tracer is blue.





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