|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 3. Effect of NrCAM on RGC axons and growth cones.(A) Overall length of RGC
axons of E6 retinal single-cell cultures grown on the indicated substrates.
Average length of axons grown on NrCAM/PLL is significantly increased compared
with those grown on PLL. Axons grown on NrCAM/Laminin/PLL are significantly
longer than those on Laminin/PLL. (B) Proportions of RGC axons grown on the
indicated substrates plotted as percentages falling into four length classes.
(C) The average growth cone size (i.e. area covered) is not significantly
different between axons extending on NrCAM/Laminin/PLL and those on
Laminin/PLL. (D) NrCAM causes a small but highly significant increase in the
growth cone perimeters on NrCAM/Laminin/PLL compared with Laminin/PLL. (E)
Growth cone perimeter divided by the square root of its area, as a measure of
protrusions and indentations formed, shows a highly significant increase on
NrCAM/Laminin/PLL compared with Laminin/PLL. Error bars represent s.d. *
P
0.05; *** P0.01.
|
