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Fig. 2. Acinar cell-specific recombination of the R26R reporter allele in
Villin-Cre pancreas. (A) Low magnification view of neonatal pancreas from a
Villin-Cre; R26R pup stained for ß-gal activity (blue) and counterstained
with Eosin. (B) High-magnification view showing lack of ß-gal activity in
islet and large duct. (C) High-magnification view showing an intralobular duct
with no ß-gal activity and all cells with a clear acinar morphology
positive for ß-gal. (D) High magnification view showing no ß-gal
staining in terminal intercalated ducts that are most closely associated with
acini. ß-Gal activity is lacking in the large blood vessel in the upper
right corner. In all panels, ß-gal activity is present in all acinar
cells. Scale bars: 10 µm. Arrows indicate pancreatic ducts. a, acinus; i,
islet; v, blood vessel.
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