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Fig. 6. Grh may prevent apoptosis of thoracic neuroblasts at late stages. (A,B) Single confocal sections of grhB37 (A) and grhB37; UAS-P35 (B) MARCM clones, showing that inhibiting cell-death caspases rescues a large neuroblast at 96 hours. (C) Histogram showing MARCM clone size for wild type (with elav-GAL4, mean=57.3, n=61, s.d.=12.7), grhB37 (with elav-GAL4, n=43, mean=28.6, s.d.=15.7) and grhB37; UAS-P35 (with elav-GAL4, n=31, mean=32, s.d.=8.6). Although elav-GAL4 driving the UAS-P35 transgene rescues the neuroblast in grhB37 clones at 96 hours, it does not significantly increase clone size. (D) Histogram showing the percentage of MARCM clones containing a large neuroblast at 96 hours (sample sizes and genotypes are as in C). elav-GAL4 driving the UAS-p35 transgene rescues the presence of a large neuroblast in >40% grhB37 clones.





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