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Fig. 7. Grh is required for maintaining but not initiating the late phase of AbdA
expression in neuroblasts. (A) At 96 hours, a neuroblast in an abdominal
H99 MARCM clone expresses Grh. (B,C) The abdominal region of a
balanced sibling control (B) and grh370 hemizygous CNS (C)
at 96 hours, showing that Mira-positive neuroblasts are normally absent by
this stage but persist when Grh activity is removed. (D) At 72 hours, a
wild-type neuroblast maintains AbdA expression but displays weak and punctate
Mira labelling, suggestive of the early stages of apoptosis. (E) At 96 hours,
a neuroblast and its last-born progeny in an abdominal H99 MARCM
clone maintain AbdA expression. (F,G) At 63 hours, Mira-positive interphase
(F) and H3p-positive M-phase (G) neuroblasts in grh370
hemizygotes express AbdA as normal. (H) At 96 hours, a Mira-positive
neuroblast from a grh370 hemizygous CNS fails to maintain
AbdA expression.