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Fig. 4. Normal appearance of the developing cortical plate in E12.5 embryos with or
without Psen1. Cresyl Violet-stained horizontal sections from E12.5 wild-type
(A,E) and Psen1–/– (B,F) embryos, as well
embryos with the nestin-Psen1 transgene on the Psen1+/+
(C,G) and Psen1–/– backgrounds (D,H). (E-H)
Higher power views through the lateral wall of the telencephalon. The
ventricular zone (VZ) and preplate (PP) are indicated. No differences were
apparent between any of the genotypes. Scale bar: 200 µm for A-D; 25 µm
for E-H.
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