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Fig. 3. Effect of ADAM17 deficiency on prenatal mammary development. (A)
Carmine-stained E18.5 mammary gland/skin whole mounts. Scale bar: 500 µm.
(B) Average number of branches in the thoracic (2 and 3) mammary glands of
Adam17/ embryos and neonates (white
circles), Egfr/ neonates (white squares) and
their respective wild-type littermates (black symbols). (C) Overall lengths of
the thoracic mammary ductal trees of Adam17/
embryos and neonates, Egfr/ neonates and
their wild-type littermates.