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Fig. 6. Flow cytometric analysis of affected bone marrow populations in Gja1Jrt/+ mice. (A) TER119+ erythroblast population was dramatically diminished in affected Gja1Jrt/+ mice compared with control littermates (+/+). (B,C) Gating of the side population (SP) of Hoechst dye effluxing cells from viable whole bone marrow, which are highly enriched in hematopoietic stem cells and primitive progenitors. (B) Young, 15-week-old and (C) 57-62 week old Gja1Jrt/+ mice exhibit an amplified population of SP cells (indicated by box) compared with control littermates (+/+), suggesting increased stem and/or progenitor cells in the affected mice.





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