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Fig. 4. Filopodial contact is important for neural crest migration through the
rostral somite. (A-D) A cell positioned midway in a chain extends filopodia
into the caudal somite and touches a cell in a chain in a different axial
level. The cell maintains filopodial contact with its chain neighbors and
returns to its original chain. (E-H) A cell attempts to extend a filopodium
into the caudal somite but all connections are lost with its neighbors in the
chain. This cell roams in a disoriented, undirected manner through the rostral
and caudal somite. Scale bars: 30 µm in A-D; 30 µm in E-H. cs, caudal
somite; D, dorsal; DRG, dorsal root ganglia; SG, sympathetic ganglia; V,
ventral.
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