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Fig. 1. Gli gene expression in mouse somites. The pattern of expression of Gli1 (A,D,G), Gli2 (B,E,H) and Gli3 (C,F,I) was compared to that of the sclerotomal marker Pax1 (J), the syndetomal marker scleraxis (K), and the myotomal marker Myf5 (L) using whole-mount in situ hybridisation in E9.5 mouse embryos. Gli1 expression is more abundant in the sclerotome (sc) and excluded from the dermamyotome, whereas Gli2 and Gli3, although initially expressed throughout the somite, rapidly become restricted to the myotome and ventral dermomyotome. Black and white arrows point to Gli expression in the sclerotome (sc), which expresses Pax1, the dorsal medial lip (dml) and ventral lateral lip (vll) of the dermamyotome, which express Myf5, and the syndetome (syn), which expresses scleraxis.





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