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Fig. 1. hedgehog mutations form an allelic series. (A) The hedgehog locus and the transgenic reporter constructs used. The lesions of four hedgehog alleles is indicated (see text). Seven transgenic constructs are drawn to a larger scale (indicated). The checks and crosses indicate the constructs that express or do not express lacZ reporter posterior to the morphogenetic furrow. The gray box indicates the minimal region required for eye-specific expression. The white triangles indicate Pointed-binding sites (this paper) and the black triangles indicate Sine oculis (So)-binding sites (Pauli et al., 2005). (B-I) Adult eyes, anterior rightwards and dorsal upwards. Genotypes are indicated below the panels. (J) Histogram of female facet counts for different hedgehog genotypes as indicated. Bars show mean facet counts; number of individuals counted indicated in bar. Error bars show the 95% confidence limits. Letters above some bars refer to panels of same genotype. Scale bar: 50 µm in B for B-I.

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