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Fig. 3. Mutations in sem-5 but not let-60 enhanced the CAN
migration defects of vab-8 mutants. The CAN positions were scored and
are displayed as described in Fig.
1. The sem-5 loss-of-function allele n2019
significantly enhanced the CAN migration defects caused by the
vab-8(gm84) allele (P<0.01). By contrast, the
let-60 hypomorphic allele n2021, the null allele
sy101sy127 and the gain-of-function allele n1046 failed to
significantly enhance the CAN migration defects of vab-8(gm84)
mutants (P=0.70, P=0.96 and P=0.21,
respectively).
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