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Fig. 3. fgf10/dae mutant embryos have reduced expression of AER markers. Lateral views of wild-type (B,E,G,K,I,M,O,S,Q,U,W) and mutant fins (C,F,H,L,J,N,P,T,R,V,X), with anterior towards left. At 28 hpf, expression of fgf24 and bmp2b appears indistinguishable in wild-type and fgf10/dae (A,D). Expression of sp8 is weakly reduced in dae (H) but sp9 (L), dlx2a (P) and wnt3l (T) expression is strongly reduced in mutants. By 38 hpf, expression of all ridge markers analysed is reduced in fgf10/dae (C,F,J,N,R,V,X) when compared with siblings (B,E,I,M,Q,U,W).





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