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Fig. 5. No significant difference in the brain sections of wild type and dnpc1a mutants. The comparison of the brain histology between a wild-type adult animal (A) and a 7-dehydrocholesterol feeding-treated dnpc1a mutant adult (B) reveals no significant difference. (C,D) Enlarged views of the central brain regions boxed in A,B, respectively. No obvious characteristic neurodegenerative vacuoles are observed in dnpc1a mutants.





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