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Fig. 6. Cell number is not crucial for angioblast migration. Transverse sections of
embryos with compromised VEGF signaling visualized for GFP (green),
ß-catenin (red) and TOPRO (blue) (A-F), and in situ hybridization with
VE-cadherin (cdh5) (G-I). The sections shown are at the level of the
6th somite (A-F). Control embryos (A,D,G), vegf MO-injected embryos
(B,E,H), plcg1 MO-injected embryos (C,F,I). The angioblasts in
embryos with compromised VEGF signaling are in a similar position to those in
control embryos, while the numbers of angioblasts are significantly reduced.
NT, neural tube; NC, notochord.
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