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Fig. 3. Redundancy of the QA motif in larval limb repression. Ventral/lateral views of T2-A2 of first larval stage cuticles with KOs shown in insets (5x, lightened, T3 and A1 only). (A) Ubx+/Ubx+, (B) Ubx{Delta}QA/Ubx{Delta}QA, (C) Ubx{Delta}QA/Ubx, (D) Ubx{Delta}QA/Ubx adb-A, (E) Ubx/Ubx, (F) Ubx abd-A/Ubx adb-A. Each thoracic segment has two three-bristle KOs. Ubx+/Ubx+ (A), Ubx{Delta}QA/Ubx{Delta}QA (B), Ubx/Ubx+ (not shown) and Ubx abd-A/Ubx+ abd-A+ (not shown) larvae never had ectopic A1 KOs. Ubx{Delta}QA/Ubx (C) larvae had up to two-bristle ectopic A1 KOs. Ubx{Delta}QA/Ubx adb-A (D) larvae had up to three-bristle ectopic A1 KOs. Ubx/Ubx (E) larvae generally had two-bristle ectopic A1 KOs but occasionally had one-bristle KOs. Ubx abd-A/Ubx adb-A (F) larvae had full three-bristle ectopic KOs on A1 through A7. Ubx+/Ubx+ larvae (A) have thin, narrow thoracic ventral denticle belts. The A2-A7 denticle belts are broad and trapezoidal, while A1 denticles belts are somewhat less broad and trapezoidal. Ubx{Delta}QA/Ubx{Delta}QA (B), Ubx/Ubx+ (not shown), Ubx abd-A/Ubx+ abd-A+ (not shown) larvae had mild transformations of the A1 denticle belts towards an intermediate T3/A1 identity. Ubx{Delta}QA/Ubx (C) and Ubx{Delta}QA/Ubx adb-A (D) larvae had more severe transformations of the A1 denticle belts to intermediate T3/A1 identity. Ubx/Ubx (E) larvae had complete transformations of the A1 denticle belts to T2 identity. Ubx abd-A/Ubx adb-A (F) larvae had complete transformations of the A1-A7 denticle belts to T2 identity. Anterior is leftwards.





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