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Fig. 8. Schematic of the developmental profile of sox10 and gnrh2
expression. (A) Dorsal view of the anterior neural plate at the 4- to 5-somite
stage (
12 hpf), depicting sox10 expression (purple) in the
pre-migratory neural crest. (B) At 18-20 hpf, there are small populations of
sox10-expressing cells on the backside of the forming optic cup
(purple). (C) At 26 hpf, the perdurance of GFP allows the visualization of the
cells previously expressing sox10 (green), which lie adjacent to
gnrh2 cells (red) or co-express gnrh2 (yellow). (D) Within
the developing midbrain at 48 hpf, the onset of sox10 expression
(purple) is adjacent to but not overlapping with the gnrh2 expression
(red).
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