|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 1. Co-expression of Sim1 and Sim2 in the developing
mammillary body. Adjacent coronal sections through the prospective MB of E10.5
(A,B), E11.5 (C,D), E12.5 (E,F) and E14.5 (G,H) wild-type embryos were
hybridized either with Sim1 (A,C,E,G) or Sim2 (B,D,F,H).
(A,B) At E10.5, Sim1 is expressed in the lateral aspect of the
neuroepithelium, which presumably corresponds to the mantle layer, but is
expressed less strongly in the medial aspect (bracket), which corresponds to
the ventricular layer (A). Sim2 is mainly expressed in this medial
domain (B). (C-F) At E11.5 and E12.5, Sim1 is expressed strongly in
the mantle layer, which corresponds to the prospective MB, but also weakly in
the ventricular layer (bracket, C). Sim2 is expressed in the ventricular layer
and in the medial aspect of the mantle layer of the prospective MB. (G,H) At
E14.5, Sim1 shows the same expression pattern. However, Sim2
expression has decreased in intensity and becomes restricted to the
ventricular layer. The arrows indicate the domains of Sim1/Sim2
expression in the prospective MB.
|
