|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
|
Fig. 10. Glial cells in mutant optic nerves have elevated levels of activated MAPK.
Sections of the proximal optic nerves from control mice (A,C) and mutant mice
(B,D) were stained with anti-P-erk. The arrow in D indicates the tumor cells
with activated MAPK. Sections from control (E) and mutant (F) optic nerves
were subjected to triple labeling with anti-P-erk (red), anti-GFAP (green) and
DAPI (blue). DAPI was used to label the nuclei. In contrast to the control
nerves where little or no cells had activated MAPK (E), mutant nerves
contained numerous P-erk positive cells, some of which co-expressed GFAP (F,
arrows) and some of which failed to express GFAP (F, arrowheads). Scale bars:
100 µm.
|
