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Fig. 1. Alignment of Cos2 sequences from insects and vertebrates. The nucleotide-
(N4, P, N2 and N3) and microtubule-binding (M1, M2) motifs in the motor domain
are different colours. The amino acid sequence corresponding to the degenerate
primer pairs used to obtain a 480 bp nucleotide fragment of zebrafish
cos2 are underlined. Accession numbers: AAB66813(Drosophila), XP_309818 (Anopheles), XP_133575 (mouse),
XP_226596 (rat, not shown) and NP_940927 (human). Sequence of all Cos2
proteins other than that of Drosophila and zebrafish are predicted by
automated computational analysis with supporting mRNA/EST evidence available
for all, except Anopheles. Predictions for Anopheles and
human Cos2 sequences are incomplete.
