spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 6. Floorplate phenotypes in mol-/- embryos are not only due to reduced Hh activity. (A,B) Lateral views of wild-type and mol-/- embryos following overexpression of exogenous shh. There is some dorsal expansion (arrowheads) of foxa expression in the midbrain of both the wild-type and the mol-/- embryo; however, foxa expression remains discontinuous and narrow along the CNS midline of the mol-/- embryo (asterisks in B). (C,D) Transverse sections of embryos in which wild-type cells were transplanted into the prospective floorplate of a mol-/- embryo (C) or mol-/- cells were transplanted into the prospective floorplate of a wild-type embryo (D). foxa is shown in blue and transplanted cells are stained brown.





Right arrow Return to article