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Fig. 4. Loss-of-function conditions of chn remove notum macrochaetae. (A,B) f^-, chn^ECJ1 homozygous clones often lose macrochaetae (black arrowheads), although they can also develop them (white arrowheads). (C) Overexpression of UAS-chni^S directed by MS248-Gal4 incompletely removes notum macrochaetae. The phenotype is similar to that of the chn^ECJ1 homozygous clones. (D) Interference with notal fusion (asterisk) and generation of extra macrochaetae (arrowheads) due to the overexpression of UAS-chn with the MS248-Gal4 driver. (E) These phenotypes are largely rescued by the coexpression of UAS-chni^S. (F,G) The number of extra macrochaetae formed by overexpressing UAS-sc is sharply reduced by simultaneous expression of UAS-chni^W (60 to 80 heminota were examined to quantify the number of bristles, as indicated in the text). No such reduction was observed when UAS-chni^W was replaced by UAS-GFP. Note the essentially complete removal of extra macro- and mesochaetae from the anterior notum (arrowheads).

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