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Fig. 6. Strategy for conditional deletion of Nmyc in the developing lung. (A) Breeding strategy to generate Sftpc-cre transgenic mice either homozygous or heterozygous for Nmycflox. (B) Typical result of genotyping lung and liver DNA. Note that the recombined Nmycflox allele was detected in the lung and not the liver. The unrecombined Nmycflox allele in the cre(+) lungs presumably derives from the mesoderm in which cre is not expressed.





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