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Fig. 3. ceh-20 and unc-62 can function independently of Hox genes lin-39 and mab-5 when positioning cells along the AP axis. The histograms show the distributions of QR.pax cells in wild-type animals as well as in ceh-20(mu290), unc-62(mu232) and lin-39(n1760) single mutants. In the double mutants ceh-20(mu290) lin-39(n1760) and unc-62(mu232); lin-39(n1760), the anteriorwards migrations of QR descendants are shortened. In unc-62(mu232); lin-39(n1760) double mutants, some cells even actively migrated towards the posterior. In the double mutants ceh-20(mu290) mab-5(e2088) and unc-62(mu232); mab-5(e2088), QR descendants did not migrate to the wild-type positions achieved in mab-5(e2088) single mutants. The vertical gray line indicates the birthplace of the QR cell. The pink arrow indicates the total anterior distance traversed by QR and its descendants giving rise to QR.pax in wild-type animals. n=100 cells for each strain.





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