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Fig. 4. Distinct profiles of ß-catenin localization associated with distinct
profiles of Myc and cyclin D1. (A)ß-Catenin immunostaining of jejunum
sections from control and mutant mice (D4), shown at low and high
magnification. (B, left) Levels of Myc and cyclin D1 transcripts in the
jejunums of control and mutant mice on day 4, as measured by RT-PCR. The level
of each transcript is expressed relative to that in wild-type mice. (B, right)
Western blot analysis of ß-catenin, Myc and Cyclin D1 in the jejunums of
control and mutant mice on day 4. (C) Myc (a,c) and Cyclin D1 (b,d) staining
in sections of jejunum from control (a,b) and mutant mice (c,d) on day 4.
Similar staining patterns were observed all along the small intestine.