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Fig. 10. KIS-L is required for the association of Pol IIoser2 with polytene chromosomes. The distribution of KIS-L (red; A,D,G,J), Pol IIa (green; B,E,H,K), Pol IIoser5 (blue; C,F) and Pol IIoser2 (blue; I.L) on chromosomes isolated from wild type (A-C,G-I) and kisk13416 mutant larvae (D-F,J-L) is shown. The levels of both Pol IIa and Pol IIoser5 are unaffected by the loss of KIS-L. By contrast, loss of KIS-L results in a dramatic reduction in the level of Pol IIoser2 associated with chromosomes.





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