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Fig. 2. Scanning electron microscopy of XEN cells and a pre-gastrula embryo. (A) Rounded XEN cell with numerous microvilli. (B) Epithelial-like XEN cell with numerous microvilli and lamellepodia at opposite ends. (C) Isolated XEN cell with a short pseudopodium. (D) Colony of XEN cells where one cell is extending several pseudopodia. (E) Isolated XEN cell with a curving pseudopodium viewed at a 60° angle. This XEN cell is on a pedestal structure and the pseudopodium is originating from below the cell. (F) E5.5 embryo with Reichert's membrane removed (inset) and a higher magnification of the anterior visceral endoderm region (broken line). Scale bars: 5 µm for A,E; 10 µm for B,C,F; 20 µm for D.





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