spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 6. Proteosome inhibition reduces neurite growth from nodose neurons. P0 nodose neurons were incubated in medium containing 10 ng/ml BDNF and either the proteosomal degradation inhibitor ALLN at a concentration of 10 µmol/l or vehicle control. Vehicle-treated neurons were also grown without BDNF. (A) Percent survival after 48 hours incubation. (B) Total neurite length after 24 hours incubation. (C) Number of branching points in neurite arbors after 24 hours incubation. (D) Sholl analysis of neurite arbor morphology after 24 hours incubation. (E) Photomicrograph of a typical ßIII tubulin-stained, vehicle-treated neuron grown for 24 hours with BDNF. (F) Photomicrograph of a typical ßIII tubulin-stained, ALLN-treated neuron grown for 24 hours with BDNF. Statistical comparisons shown are with respect to the control transfected neurons, *P<0.05, **P<0.001. Scale bars: 50 µm.





Right arrow Return to article