First published online March 7, 2005
Development 132, 702e (2005)
© The Company of Biologists Limited
Making a bird's crowning glory
Feathers are a defining feature of birds but their size, colour, shape and
arrangement varies widely between species. Feather morphogenesis involves
reciprocal signalling between the dermis and epidermis of the feather bud, but
it is unclear how species-specific feather differences are generated. Now,
Eames and Schneider report that premigratory neural crest cells transplanted
from quails into ducks form dermis that instructs the host epidermis to form
quail-like feather buds, and vice-versa (see
p. 1499). Quail and
duck have distinct feather patterns and divergent growth rates. The
researchers show that in quail-duck chimeras, donor neural-crest-derived
dermis alters the spatial pattern and time of formation of host cranial
feathers by altering the expression of members and targets of the bone
morphogenetic protein, sonic hedgehog and delta/notch pathways. The
researchers suggest that this marked spatiotemporal plasticity in feather
development might facilitate feather evolution.

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Related articles in Development:
- Quail-duck chimeras reveal spatiotemporal plasticity in molecular and histogenic programs of cranial feather development
- B. Frank Eames and Richard A. Schneider
Development 2005 132: 1499-1509.
[Abstract]
[Full Text]