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Fig. 7 sp5l RNA overexpression rescues wnt3a morphants. Embryos are shown at 48 hpf, with arrows marking the posterior end of the notochord. (A) wnt3a MO embryos co-injected with 200 pg of a control RNA (renilla luciferase) typically have a truncated notochord (89%, n=104). (B) Most embryos co-injected with wnt3a MO and 200 pg sp5l MO have normal tail development (33% have truncated notochord; n=107). (C) Graph showing penetrance of rescue.





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