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Fig. 2. The cells responsive to DC5 activity in Drosophila are the cone
cells. The activity pattern of DC5(8x) in the adult compound eye (A) and in
the larval eye imaginal disc (B) was compared with the activity pattern of the
cone-cell-specific enhancer SME (C,D). SME is the minimal eye-specific
enhancer of D-Pax2 (Flores et
al., 2000). Fluorescence microscopy indicates that both activity
patterns are identical, as shown in preparations of the larval eye imaginal
disc (E,F,G) and in cryosections of the adult compound eye (H,I,J). When a
signal-peptide-tagged EGFP was used as a reporter for the enhancer activity,
the fluorescence signal was detected in the lenses of the compound eye (K).
This experiment was done in a w+ genetic background to
keep the ommatidium structure unaltered (L).
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