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Fig. 5. Properties of the X-box motif in C. elegans. (A) The X-box consensus sequence obtained from in vivo expression analysis. Nucleotides marked in red are strongly conserved and important for the proper function of the motif. (B) Proposed scheme for the difference in expression patterns observed for xbx genes. Depending on the nucleotide composition of the X-box, DAF-19 can bind to the motif either in homodimer (driving expression in many, most or all CSN) or in heterodimer form, interacting together with some cell-specific factor (driving expression in a subset of CSN).





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