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Fig. 8. Model for ALR-1 functions in the AWA/ASG sensory and VD/DD MNs. (A) ALR-1 acts in parallel to UNC-130 and upstream of LIN-11 to specify the AWA and ASG neurons. ALR-1 may act in the precursors or earlier in the lineage. (B) ALR-1 and UNC-55 act in parallel to regulate flp-13::gfp expression in the VD MNs. The function of ALR-1 in the DD MNs is unclear. UNC-55 also acts to specify the correct synaptic connectivities of the VD MNs. Expression of the unc-25 GAD and unc-47 vesicular GABA transporter genes is regulated by the UNC-30 HD protein (see text for references).





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