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Fig. 4. dronc is essential for cell death in wing and eye development. (A,B) Abnormal wing phenotype of homozygous adult dronc mutants. The wings are less transparent and curved. The held-out wing in A is occasionally observed and not typical. Genotype: (A) droncI24/droncI24; (B) droncI29/droncI29. (C) en::GFP expression in a wing of a freshly eclosed wild-type male (less than 1 hour old). (D) en::GFP expression in a wing of a 24-hour-old wild-type male. No GFP expression is detectable. (E) en::GFP expression in a wing of a 24-hour-old droncI24/droncI29 male. GFP expression is still detectable. (F) Anti-Dlg labeling in a wild-type pupal retina disc to visualize cell outline. (G) Anti-Dlg expression in pupal retina of a droncI24 mutant clone. Additional inter-ommatidial cells are present, suggestive of lack of apoptosis.





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