spacer gif spacer gif spacer gif spacer gif ARCHIVE ANNOUNCEMENT! spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 7


Fig. 7. Increased Hippo signaling, but not cell competition, controls apoptosis in vps25 clones. (A-C) Caspase-3*-labeling of vps25 mosaics (genotype: ey-FLP; FRT42D vps25N55/FRT42D arm-lacZ M(2)) in a Minute (M) background. Caspase-3* activity is unaffected. Clones are marked by the absence of ß-Gal staining. (D-F) Caspase-3*-labeling of GFP-marked vps25/dMyc mosaics (hs-FLP UAS-GFP; FRT42 vps25N55/FRT42D tub-Gal80; tub-Gal4/UAS-dMyc). Caspase-3*-activity is unaffected. (G-I) Expanded (Ex) labeling of GFP-marked vps25 mosaics (hs-FLP UAS-GFP; FRT42D vps25N55/FRT42D tub-Gal80; tub-Gal4). Ex protein levels are reduced in vps25 clones (arrow), indicating increased Hippo activity. (J-L) Caspase-3*-labeling of GFP-marked vps25 hippo double mutant mosaics (hs-FLP UAS-GFP; FRT42D vps25N55 hippo3D/FRT42D tub-Gal80; tub-Gal4). Caspase-3* activity is blocked.





Right arrow Return to article