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Figure 10


Fig. 10. C. elegans DAPC and dgn-1 mutants have distinct behavioral phenotypes. (A) Hypercontraction of the head musculature (arrowhead, arrow) in DAPC component mutants dys-1(cx18) and dyb-1(cx36), but not in dgn-1(cg121), during movement on plates. (B) Double mutants of dgn-1 and DAPC components show hypercontraction. (C) Activity (body bends per minute) during movement on agar plates or during thrashing in liquid. Measurements were normalized to wild-type (wt) values (plate movement, 100%=30.1 bends/minute; thrashing, 100%=167.9 bends/minute). Both dgn-1(cg121) and DAPC mutants are hyperactive, but double mutants show wild-type or lower rates. (D) Prolongation of the Pboc-to-Pboc defecation cycle time in the dgn-1(cg121) and in dgn-1;dys-1 double mutants, but not in the dys-1(cx18) mutant itself. In C and D, the mean and standard deviation (error bars) of 8-10 animals is reported.





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