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Fig. 3. Testicular degeneration in Bmp4S2G/S2G adults.
(A) Isolated testes from age matched wild-type and
Bmp4S2G/S2G adult males. (B,C) Hematoxylin
and Eosin-stained sections from age matched adult testis. (D-G) DAPI
staining (D,F) and TUNEL staining (E,G) of sections from age matched adult
testes. (H,I) Hematoxylin and Eosin-stained P6 testis sections
from wild-type and mutant littermates. (J) Western blots of equivalent
amounts of protein from wild-type and mutant P6 testes probed with an antibody
directed against the mature domain of BMP4. The blot was reprobed for actin as
a loading control.