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Fig. 3. A sens genomic transgene can partially rescue the adult PNS phenotypes of sens mutant flies when Zn finger 1 is mutated. (A) Bristles fail to develop in sens^E2 mitotic clones generated by the C684-Gal4 driver (see Materials and methods). (B) sens-g is able to rescue all bristles in sens^E2 mitotic clones (bristles in clones are marked with yellow). (C) sens-1CCg is able to rescue some of the bristles in sens^E2 mitotic clones. (D) sens-3CCg fails to rescue the bristle loss in sens mutant clones. Arrows in C,D indicate lost macrochaetae; the arrowhead in C indicates a rescued macrochaetae. Mutant areas in A-D are marked with white lines. (E) Quantification of number of post-orbital bristles formed in flies that have large sens mutant clones generated by the eyeless-FLP system. Error bars represent the standard error of the mean. y w was used as the wild-type (WT) strain. For each genotype, post-orbital bristles of 7-24 flies were counted. The differences among `no transgene', sens-2CCg and sens-3CCg are not statistically significant, neither are the differences among wild type, sens-g and sens-4CCg. However, the bristle number for sens-1CCg is significantly different from all other genotypes and again shows partial rescue (P<0.0001).

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