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Figure 4


Fig. 4. Expression of the hybrid Gbx2 transcript recapitulates wild-type Gbx2 expression. (A-H) Lateral views of embryos (A-E) or dorsal views of the cerebellar primordium (CEP; F-H) of the genotype and developmental stage indicated stained by whole-mount ISH for the wild-type Gbx2 (A,C,F) or hybrid transcript (B,D,E,G,H). Gbx2 hybrid mRNA (G,H) and wild-type Gbx2 mRNA (F) are similarly expressed throughout the CEP. Note the increased expression of the hybrid transcript in Gbx2neo homozygotes (H) compared with Gbx2neo heterozygotes (G), and its absence in wild-type embryos (E).





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