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Figure 5


Fig. 5. Microarray analysis of basonuclin-deficient oocytes. Oocyte RNAs from four non-transgenic and six transgenic mice were analyzed using Affymetrix Mouse Genome GeneChip MOE 430 v2. Raw microarray data were processed by the GC-RMA or MAS 5 program and analyzed with SAM, GeneSpring and EASE software. (A) A sample clustering analysis showed a high degree of association within the control and transgenic groups. (B) Pathway analysis grouped the upregulated genes into four processes, and that of the downregulated into three. The percentage of each group in the up- or downregulated category is indicated by the length of the bar (black for upregulated and white for downregulated).





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